Longitudinal Serum Creatinine Levels in Relation to Graft Loss Following Renal Transplantation: Robust Joint Modeling of Longitudinal Measurements and Survival Time Data

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longitudinal serum creatinine levels in relation to graft loss following renal transplantation: robust joint modeling of longitudinal measurements and survival time data

conclusions graft failure is more likely to occur in patients with higher serum creatinine levels. results there was a positive association between the serum creatinine level and graft failure (hr = 5.13, p < 0.001). a one unit increase in the serum creatinine level suggests an increased risk of graft failure of up to 5.13 times. the serum creatinine level significantly decreased over time (95%...

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Longitudinal Serum Creatinine Levels in Relation to Graft Loss Following Renal Transplantation: Robust Joint Modeling of Longitudinal Measurements and Survival Time Data

BACKGROUND Chronic kidney disease (CKD) is a major public health problem that may lead to end-stage renal disease (ESRD). Renal transplantation has become the treatment modality of choice for the majority of patients with ESRD. It is therefore necessary to monitor the disease progression of patients who have undergone renal transplantation. In order to monitor the disease progression, the conti...

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longitudinal assessment of serum creatinine levels on graft survival after renal transplantation: joint modeling approach

conclusions the major finding of this study is that one unit increase in serum creatinine level suggests an increased risk of graft failure of up to four times. patients and methods this study was carried out at the department of nephrology, baqiyatallah hospital, baqiyatallah university, tehran, iran, between april 2005 and december 2008. during that time period, 461 patients who had undergone...

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Longitudinal Assessment of Serum Creatinine Levels on Graft Survival After Renal Transplantation: Joint Modeling Approach

BACKGROUND Chronic kidney disease (CKD) is a major public health problem. The eventual outcome of CKD is end-stage renal disease (ESRD). Early diagnosis and proper management play an important role in preventing CKD progression to ESRD. Dialysis and kidney transplantation are the only treatment options available for patients suffering from ESRD. OBJECTIVES This study was designed to investiga...

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Bayesian Sample Size Determination for Joint Modeling of Longitudinal Measurements and Survival Data

A longitudinal study refers to collection of a response variable and possibly some explanatory variables at multiple follow-up times. In many clinical studies with longitudinal measurements, the response variable, for each patient is collected as long as an event of interest, which considered as clinical end point, occurs. Joint modeling of continuous longitudinal measurements and survival time...

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ژورنال

عنوان ژورنال: Nephro-Urology Monthly

سال: 2016

ISSN: 2251-7006,2251-7014

DOI: 10.5812/numonthly.39292